This video outlines three core learning principles to accelerate knowledge acquisition and retention: embracing the inherent challenge of learning, actively engaging with material through 'learning by doing' (like playing a video game), and strategically combating the forgetting curve. It emphasizes using spaced repetition, facilitated by tools like flashcard apps and revision calendars, and interleaving different topics to foster deeper brain connections for long-term memory. By adopting these methods, learners can overcome initial struggles and achieve mastery more efficiently, appearing like a genius.